FDA approved PEGylated drug

To date, eleven PEGylated proteins, antibody fragments, oligonucleotides, and small molecules have been approved by FDA are on the market, including PEGylated bovine adenosine deaminase: pegademase bovine (Adagen); and PEGylated l-asparaginase: pegaspargase (Oncaspar); PEGylated products of interferon-alpha (IFN-alpha): peginterferon-2b (PegIntron) and peginterferon-2a (Pegasys); PEGylated granulocyte colony stimulating factor (GCSF): pegfilgrastim (Neulasta); PEGylated growth hormone receptor antagonist: pegvisomant (Somavert); PEGylated a 28-nucleotide aptamer against vascular endothelial growth factor (VEGF); Pegaptanib sodium (Macugen); continuous erythropoietin receptor activator Mono-mPEG-epoetin- (Mircera); PEGylated Fab fragment of the humanized anti-tumor necrosis factor (TNF)-alpha monoclonal antibody certolizumab pegol (Cimzia); PEGylated recombinant porcine uricase (urate oxidase) (Puricase); and pegylated naloxol (naloxegol) (Movantik).

FDA approved PEGylated drug

Current Drug Research on PEGylation with Small Molecule Agents, Progress in Polymer Science, 2013, 38, 421-444

Creative PEGWorks offers the most comprehensive collection of PEGylation reagents and PEG derivatives for the drug research community.

This entry was posted in Blogs, PEGylated Products on Market, pegylation, PEGylation Success Stories and tagged , , , . Bookmark the permalink.

1 Response to FDA approved PEGylated drug

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s